Bupropion is an antidepressant medication used to
treat major depressive disorder and seasonal affective disorder. The Zyban
brand of bupropion is used to help people stop smoking by reducing cravings and
other withdrawal effects.
Bupropion comes as a tablet and a sustained-release or
extended-release (long-acting) tablet to take by mouth. The regular tablet
(Generic Wellbutrin 150mg) is usually taken three times a day, with doses at least 6 hours
apart, or four times a day, with doses at least 4 hours apart. The
sustained-release tablet (Wellbutrin SR, Zyban) is usually taken twice a day,
with doses at least 8 hours apart. The extended-release tablet (Aplenzin,
Wellbutrin XL) is usually taken once daily in the morning; doses of the
extended-release tablet should be taken at least 24 hours apart. When bupropion
is used to treat seasonal affective disorder, it is usually taken once a day in
the morning beginning in the early fall, continuing through the winter, and
stopping in the early spring. Sometimes a lower dose of bupropion is taken for
2 weeks before the medication is stopped. Take bupropion with food if the
medication upsets your stomach. If you have trouble falling asleep or staying
asleep, do not take bupropion too close to bedtime. Take bupropion at around
the same time(s) every day. Follow the directions on your prescription label
carefully, and ask your doctor or pharmacist to explain any part you do not
understand. Take bupropion exactly as directed. Do not take more or less of it
or take it more often than prescribed by your doctor.
Bupropion is also sometimes used to treat episodes of
depression in patients with bipolar disorder (manic depressive disorder; a
disease that causes episodes of depression, episodes of mania, and other
abnormal moods) and to treat attention deficit hyperactivity disorder (ADHD;
more difficulty focusing, controlling actions, and remaining still or quiet
than other people who are the same age). Talk to your doctor about the possible
risks of using this medication for your condition.
Bupropion may cause side effects. Tell your doctor if
any of these symptoms are severe or do not go away:
- drowsiness
- anxiety
- excitement
- difficulty falling asleep or staying asleep
- dry mouth
- dizziness
- headache
- nausea
- vomiting
- stomach pain
- uncontrollable shaking of a part of the body
- loss of appetite
- weight loss
- constipation
- excessive sweating
- ringing in the ears
- changes in your sense of taste
- frequent urination
- sore throat
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